Frequently Asked Questions

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Is your Methylene Blue safe?

Our Methylene Blue is USP (Pharmaceutical) Grade. Every batch is tested by an independent laboratory; the current Bilacon report covers heavy metals and microbiology and describes the results as unremarkable. You can see the full report on our lab results page. No fillers are added.

We place a lot of importance on the purity of our products and the quality of our ingredients, and use the highest quality suppliers and manufacturers in Europe.

Before you buy however, please do refer to our health disclaimer.

What is the safe way to take Methylene Blue?

Disclaimer : This product is not intended to diagnose, treat, cure, or prevent any disease. This information is for educational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional before beginning any new supplement regimen.

Important Considerations :

  • Do not exceed recommended amounts found in peer-reviewed literature without medical supervision.
  • Do not use methylene blue concurrently with SSRIs, SNRIs, MAOIs, or any drug that affects serotonin.
  • Not for use by individuals who are pregnant, breastfeeding, or have G6PD deficiency.

General Information : Methylene Blue may support cellular energy production and brain health. However, effects can vary based on physiology, body weight, sensitivity, and concurrent supplement or medication use.

For information on dosing from an MD: Jonas Kuehne MD on Methylene Blue dosing and safety

How long does shipping take?

We aim to have your order fulfilled and ready to be shipped within 24 hours on a business day. We ship from Europe, so the estimated shipping time varies on your location - please see our Shipping Policy.

Is Methylene Blue FDA-approved?

Methylene blue is FDA-approved in one specific form: a prescription injection (ProvayBlue®) used in hospitals to treat acquired methaemoglobinaemia. VitaBlue products are not that medicine, are not FDA-approved and are sold for research use only. Methylene blue itself has been the subject of more than 18,000 published studies.

Do you have a risk-free guarantee?

If you do not feel our products helped or are unhappy in any way, please Contact Us, and we will make it right. That's a promise.

How much Methylene Blue should I start with?

Studies show doses between 5 mg - 15 mg are effective and 90% of people report 5 mg to be their go-to dose, however we would recommend to start with a much smaller dose of 1mg.

Please start small, and consult our blog post on proper dosages and administration, as well as our Health Disclaimer.

Does Methylene Blue break a fast?

Methylene blue itself contains no calories. Research in cells and animals suggests it may interact with fasting-related processes such as mitophagy; this has not been established in people. We covered the research on our blog post.

Will Methylene Blue make my pee green and my tongue blue?

Yes! This is normal (and temporary!). It will vary from day to day depending on the dose, hydration levels, micronutrients in your food intake and how you administer it. Methylene Blue is a very strong blue dye and should be treated carefully, we covered everything on safe handling, doses, administration and even taste in our blog post.

Will Methylene Blue make my brain blue?

No, if you've heard this thrown around, it's nothing but fear-mongering. This has only happened with extremely high dosages in very specific circumstances (i.e MB was used to try revive people in a state of septic shock, in a very high IV dose, and it wasn't metabolised properly as organs weren't functioning. PMID: 32940886). See here an explanation from Dr. Scott on the issue.

Info & Research

How to Store Methylene Blue: Light, Heat, Shelf...

Methylene blue is stable when you treat it right and messy when you don't. How to store it for maximum shelf life, and how to handle the inevitable blue stain.

How to Store Methylene Blue: Light, Heat, Shelf...

Methylene blue is stable when you treat it right and messy when you don't. How to store it for maximum shelf life, and how to handle the inevitable blue stain.

Methylene Blue and Caffeine: Energy Without the...

Caffeine spikes you, then drops you. Methylene blue works a level deeper. Here's how the two differ, how people stack them, and where to be careful.

Methylene Blue and Caffeine: Energy Without the...

Caffeine spikes you, then drops you. Methylene blue works a level deeper. Here's how the two differ, how people stack them, and where to be careful.

How to Read a Methylene Blue Certificate of Ana...

Not all methylene blue is safe to ingest. Here is how to read a Certificate of Analysis, what USP grade really means, and the red flags that separate pharmaceutical purity...

How to Read a Methylene Blue Certificate of Ana...

Not all methylene blue is safe to ingest. Here is how to read a Certificate of Analysis, what USP grade really means, and the red flags that separate pharmaceutical purity...

Methylene Blue Dosage: How to Titrate Low and Slow

A beginner-friendly framework for methylene blue dosing: why less is more, how per-drop micro-dosing works, and the safety rules that matter before you start.

Methylene Blue Dosage: How to Titrate Low and Slow

A beginner-friendly framework for methylene blue dosing: why less is more, how per-drop micro-dosing works, and the safety rules that matter before you start.

Methylene Blue Drops vs Nano Spray — Which One ...

Two formats, same lab-tested methylene blue. Which one fits your routine? Side-by-side cost, dose, and use-case breakdown.

Methylene Blue Drops vs Nano Spray — Which One ...

Two formats, same lab-tested methylene blue. Which one fits your routine? Side-by-side cost, dose, and use-case breakdown.

Methylene Blue for Depression and Mood: What th...

Methylene blue has clinical trial data on depression going back to the 1980s — predating most modern antidepressants. It's one of the least talked-about aspects of MB, but potentially one...

Methylene Blue for Depression and Mood: What th...

Methylene blue has clinical trial data on depression going back to the 1980s — predating most modern antidepressants. It's one of the least talked-about aspects of MB, but potentially one...