VitaBlue Methylene Blue Drops | 30ml | USP Grade
VitaBlue Methylene Blue Drops | 30ml | USP Grade
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Methylene Blue Drops — 150 mg in 30 ml, USP pharmaceutical grade.
Sourced and manufactured in Europe. Third-party lab tested every batch — no fillers, no heavy metals, no shortcuts. The glass dropper gives you precise micro-dosing (about 250 mcg per drop) so you can dial in exactly what works for you.
Two ingredients: Methylene Blue USP and distilled water. Nothing else.
Most users start with 1–3 mg in the morning and adjust from there.
See the full certificate of analysis for the current batch: Latest lab results →
Want the same Methylene Blue in a travel-friendly spray? See VitaBlue Nano →
Benefits
Benefits
Benefits
What USP Grade Methylene Blue is being studied for
Energy & Metabolism
- Mitochondrial support: Studied for its role in supporting ATP production at the mitochondrial level.
- Metabolic cofactor: Investigated for its interaction with the body's electron-transport chain.
Cognition & Brain Health Research
- Studied for focus and memory: Of active interest in neuroscience research on attention, working memory, and executive function.
- Electron-carrier properties: Researched in the context of neuronal energy metabolism.
Mood & Cognitive Performance Research
- NAD+/NADH cycling: Studied for its interaction with redox pathways linked to brain energy metabolism.
- Research-stage interest: Of ongoing interest in mood and cognitive-performance studies.
Cellular Health & Antioxidant Activity
- Redox cycler: Acts as both an electron donor and acceptor — the mechanism behind its antioxidant role.
- Oxidative stress research: Studied for its role in managing cellular oxidative stress.
Backed by 18,000+ peer-reviewed studies. This product is for research use only — see our Health Disclaimer. Not intended to diagnose, treat, cure, or prevent any disease. Always consult a healthcare professional first.
Ingredients
Ingredients
- Methylene Blue (150 mg), European Sourced, USP (Pharmaceutical) Grade
- Purified Water (30 ml), USP (Pharmaceutical) Grade
Both thoroughly lab tested with transparent results - see second image.
Directions
Directions
Measurements (approximate):
1 drop : ±250mcg
Full dropper : ±5mg
Most user start with 1-3mg daily and work up to 5mg.
Take it in the morning or early afternoon.
Drop onto the back of the tongue, or mix into water or juice.
Substance will stain surfaces & tongue temporarily unless mixed with juice or water.
For a full guide on dosages, timing, administration and more, please click here.
Please note, this product is for research use only, all users should be aware of our Health Disclaimer, and consult with a healthcare professional first.
Shipping & Returns
Shipping & Returns
Please see our Refund Policy and Shipping Policy
USP Grade (Highest Purity)
Sourced & Made in Europe
Third-Party Lab Tested
Pharmaceutical Grade vs Aquarium Methylene Blue
Same molecule. Completely different product. The difference is a purity standard you can't see on the label — and it's the reason cheap Methylene Blue is cheap.
| VitaBlue USP Grade | Aquarium / Industrial | |
|---|---|---|
| Purity standard | Meets the US Pharmaceutical standard | No published standard |
| Lab testing | Independent lab, every batch | Not required |
| Made for | Human supplement use | Dyeing fabric, staining slides, fish tanks |
| Heavy metals | Tested against strict limits | Possible, and unmeasured |
| What's inside | Two things. Methylene Blue and distilled water | Usually undisclosed |
| Looks like | Deep blue liquid | Deep blue liquid |
That last row is the problem. You cannot tell them apart by looking.
What's In The Bottle
No preservatives. No sweeteners. No alcohol. No carrier oils. Which is also why it needs to stay sealed and out of direct light.
Methylene Blue Side Effects And Drug Interactions
Methylene Blue is an MAO inhibitor. Read this before your first dose.
Taken with antidepressants, it can trigger serotonin syndrome — a real and potentially serious reaction. The US FDA issued a formal safety warning about this in 2011.
Do not take Methylene Blue with SSRIs, SNRIs, MAOIs or tricyclic antidepressants without talking to your doctor first.
Also avoid if you have G6PD deficiency, if you're pregnant or breastfeeding, or if you're under 18.
Blue or green urine is normal and harmless.
This product is not intended to diagnose, treat, cure or prevent any disease. Nothing here is medical advice. If you take prescription medication or have a medical condition, speak to a qualified healthcare professional before use.
Common Questions
What is Methylene Blue?
A synthetic blue compound first made in 1876. It dissolves in water and turns a deep blue. It's listed in the United States Pharmacopeia, which sets an official standard for how pure it has to be and how much of any contaminant is allowed.
That standard is what "USP grade" actually means. It's a lab specification with numbers behind it, not a phrase a brand can give itself.
What's the difference between USP grade and aquarium Methylene Blue?
Purity, and nothing you can see. Aquarium and lab-stain Methylene Blue is made to industrial grade — manufactured to be blue, not manufactured to a purity standard. It can carry heavy metal residues that don't matter when you're treating a fish tank.
USP grade is tested against published limits. Same colour, different contaminant profile.
How much Methylene Blue should I take?
Most people start with 1–3 mg in the morning and adjust from there. One drop is around 250 mcg, so 4 drops is roughly 1 mg.
Always dilute in water first. Speak to a healthcare professional before starting, particularly if you take any prescription medication.
Can you take Methylene Blue with antidepressants?
Not without medical supervision. Methylene Blue is an MAO inhibitor, and combining it with SSRIs, SNRIs, MAOIs or tricyclics risks serotonin syndrome. The FDA has issued a formal warning on this. Talk to your doctor before combining anything.
Does Methylene Blue stain your teeth?
Undiluted, yes — it's a dye. Always dilute it in water and drink it rather than dropping it straight onto your tongue. It will also stain fabric and worktops, permanently on anything porous. Rinse whatever it touches straight away.
Why does Methylene Blue turn your urine blue?
Because it's a dye, and your body clears what it doesn't use through the kidneys. Blue or blue-green urine is expected and harmless.
How long does one bottle last?
About 600 drops at roughly 250 mcg each. At 1 mg a day — four drops — a 30 ml bottle lasts around five months.
Why glass instead of plastic?
Methylene Blue is light-sensitive and stains plastic. Glass protects the liquid and lets you see how much is left without opening it.
Should I get the drops or the spray?
Drops if it lives at home — the glass dropper gives you finer control over the dose. Nano spray if it travels with you, because a glass dropper in a bag is a bad idea. Same liquid, same strength, both ways.
What the Experts Say
-
Dr. Ray Peat, PhD
Source"[MB is] a good anti-inflammatory... quite a few people are having very powerful anti-depression effects from it with just one milligram a day"
"[MB] has this remarkable range of biologically valuable functions... it's a supplement you can take that will actually improve your cellular energy function"
-
Dr. Eric Berg, Ph.D
Source"MB helps the mitochondria absorb and transport oxygen. It actually improves how the body uses oxygen. MB has the ability to remove or add electrons depending on what part of the body needs them... anything that involves mitochondrial dysfunction can benefit from MB"
-
Gary Brecka, Human Biologist
Source"MB shows signs as a potent nootropic... studies show it can enhance memory, focus and executive function... it's believed to do this by increasing mitochondrial efficiency... and promoting the production of ATP. This is crucial as improved mitochondrial function is directly linked to enhanced brain health and cognitive performance."
Drops or Nano? Quick comparison
| Drops | Nano | |
|---|---|---|
| Format | 30 ml glass dropper | 15 ml travel spray |
| Methylene blue | 150 mg | 75 mg |
| Dose per unit | ~0.25 mg per drop | ~0.333 mg per spray |
| Best for | Daily home use | Travel, gym, on-the-go |
| Lasts (at 2 mg/day) | ~10 weeks | ~5 weeks |
| Price (without offers) | €32.95 | €24.95 |
| Price per mg | €0.22 | €0.33 |
Most cost-effective for daily use: Drops. Most convenient for travel: Nano. Many regulars keep one of each.
FAQ
Is your Methylene Blue safe?
Yes. Our Methylene Blue is USP (Pharmaceutical) Grade and thus meets the highest purity standard. Every batch is third-party lab tested and found to be heavy-metal and toxin free. You can see the lab results as one of the product pictures above. No fillers are added.
We place a lot of importance on the purity of our products and the quality of our ingredients, and use the highest quality suppliers and manufacturers in Europe.
Before you buy however, please do refer to our health disclaimer.
What is the safe way to take Methylene Blue?
Disclaimer : This product is not intended to diagnose, treat, cure, or prevent any disease. This information is for educational purposes only and does not constitute medical advice. Always consult with a qualified healthcare professional before beginning any new supplement regimen.
Important Considerations :
- Do not exceed recommended amounts found in peer-reviewed literature without medical supervision.
- Do not use methylene blue concurrently with SSRIs, SNRIs, MAOIs, or any drug that affects serotonin.
- Not for use by individuals who are pregnant, breastfeeding, or have G6PD deficiency.
General Information : Methylene Blue may support cellular energy production and brain health. However, effects can vary based on physiology, body weight, sensitivity, and concurrent supplement or medication use.
For information on dosing from an MD: Jonas Kuehne MD on Methylene Blue dosing and safety
How long does shipping take?
We aim to have your order fulfilled and ready to be shipped within 24 hours on a business day. We ship from Europe, so the estimated shipping time varies on your location - please see our Shipping Policy.
Is Methylene Blue FDA-approved?
No, as of now it is approved for research purposes only. It is, however, backed by 18,000+ studies.
Do you have a risk-free guarantee?
If you do not feel our products helped or are unhappy in any way, please Contact Us, and we will make it right. That's a promise.
How much Methylene Blue should I start with?
Studies show doses between 5 mg - 15 mg are effective and 90% of people report 5 mg to be their go-to dose. That’s just 20 drops from our tincture, or 15 sprays from Nano! However, please start small, and consult our blog post on proper dosages and administration, as well as our Health Disclaimer.
Does Methylene Blue break a fast?
No, it actually synergises and speeds up the effects of a fast! Mitophagy is sped up by combining MB and fasting, we covered this on our blog post.
Will Methylene Blue make my pee green and my tongue blue?
Yes! This is normal. It will vary from day to day depending on the dose, hydration levels, micronutrients in your food intake and how you administer it. Methylene Blue is a very strong blue dye and should be treated carefully, we covered everything on safe handling, doses, administration and even taste in our blog post.
How is this different from Nano?
Both products use the same USP-grade methylene blue. Drops come in a 30 ml glass dropper bottle (150 mg total) — best for at-home daily use and precise dose-by-dose control. Nano is a 15 ml travel spray (75 mg total) — best for on-the-go, no measuring, no leaks.
How long does a bottle last?
A 30 ml bottle holds roughly 600 drops. At a typical 1–3 mg daily dose (4–12 drops), a single bottle lasts most users between 7 and 12 weeks.
Why USP grade matters
USP (United States Pharmacopeia) is the highest purity standard. It guarantees the methylene blue is free of heavy metals, contaminants, and fillers. Industrial-grade methylene blue (sold for aquariums or fabric dye) is *not* the same product and should never be consumed.
How quickly does it work?
Most users report noticing effects within 15–30 minutes of taking it on an empty stomach. Effects typically last 4–6 hours.
Will it stain things?
Yes. Methylene blue is a strong dye. Use the dropper carefully, avoid white fabric and surfaces, and rinse glassware immediately after use. Mixing with water or juice (instead of dropping directly on the tongue) reduces — but doesn't eliminate — tongue staining.
Can I take it with coffee?
There's no known interaction between methylene blue and caffeine. Many users take both. The relevant interaction warning is with SSRIs, SNRIs, MAOIs, and other serotonergic drugs — see our dosing guide and Health Disclaimer.
How do you ship?
Orders placed before our daily cutoff ship within 24 business hours from the Netherlands. EU delivery is typically 2–5 business days. International delivery varies — see our Shipping Policy.
